Systems Biology

Networks   -   Synchronization    -   Signals

All living systems (insects, animals [humans] and plants) function as a SYSTEM - an intimately connected NETWORK of cells and organ tissue sub-systems that are:
- Self-Regulatory; optimally functioning within homeostatic zone through Sensing and Responding
- continuously communicating-responding within itself via back-and-forth "crosstalk" of SIGNALS
- continuously monitoring its external environment and integrating this information into its Sensing and Responding.
Living systems have multiple complex processes (biochemical, physiological, and behavioral) that are ORGANIZED in distinctive PATTERNS - across an almost infinite range of time scales (from sub-cellular, to cellular, to tissue, to organ system, to whole person, to circadian, to lifespan).
These patterns are SYNCHRONIZED across all these time-scales and across the entire living system.

Tavassoly (2018)  Systems biology primer: the basic methods and approaches  Essays Biochem. Overview of current experimental and computational methods used in systems biologyO

Ma'ayan (2017) Complex Systems  Outline of general design principles of complex systems - particularly in humans.